prepFAST Preparing for USP <232> <233> Through Automation

Introduction  |  Oral Drugs by Dilution  |  Oral Drugs by Dissolution  |  Inhalation Undiluted  |  Parenteral Undiluted

The prepFAST inline autodilution system with ICP-MS fully automates USP <233> sample dilutions and J based calibrations. The prepFAST automatically:

  1. dilutes a single stock standard to build linear calibration curves surpassing all USP<233> validation criteria
  2. dilutes samples to the appropriate Total Dissolved Solids (TDS)


  • Autocalibration from a single J stock standard
  • Auto Sample Dilution
  • Priority Sample Dilution
  • Daily walk-up and analyze ICP-MS instrument for USP
  • Perfect for laboratories new to ICP-MS
  • Automate labor intensive steps to significantly reduce notebook entries


  • prepFAST all flows syringe-driven
       - Eliminate peripump tubing daily maintenance
  • prepFAST autocalibration
       - Single multi-element standard for all J values
  • prepFAST auto inline dilution
       - Eliminate final manual dilution step
  • Brings samples to constant total dissolved solids (0.2%)
  • Easy-to-use automated system for USP protocols
  • Pre-developed fully automated methods
  • Exceeds all USP validation criteria: Stability, Repeatability, Ruggedness, and Accuracy
  • Well-suited to the demands of a high throughput pharmaceutical laboratory